Marco Bezzecchi returned to the top step of a MotoGP Sprint Race podium for the first time since the 2023 Dutch TT.
After qualifying in pole position, Marco Bezzecchi was able to convert his starting position into his first Sprint victory of the 2025 MotoGP season as he claimed victory at his home circuit.
The closest challenger to Bezzecchi at the chequered flag was the BK8 Gresini Racing MotoGP rider, Alex Marquez, who crossed the line in second place, but was one second behind Bezzecchi.
For the third time this season, Fabio di Giannantonio featured on a MotoGP Sprint Race podium as he finished third at the VR46 Racing Team's home event.
Franco Morbidelli could not match his teammate as he finished in fourth place, but completed a solid day for the VR46 Racing Team.
The top KTM rider was Pedro Acosta, as he took a fifth-place finish for the Red Bull KTM Factory Racing squad in the San Marino Sprint Race.
Fermin Aldeguer was back in the points in a MotoGP Sprint Race as he took the BK8 Gresini Racing MotoGP machine to a sixth-place finish.
After starting from the second row of the grid, Luca Marini was able to take his Honda HRC Castrol RC213V to a points-scoring finish as he crossed the line in seventh.
The reigning MotoGP World Champion, Jorge Martin, scored points in a Sprint Race for the second time this season as he finished in eighth place on the Aprilia.
Taking the final points scoring position was the Trackhouse Racing rider, Raul Fernandez, who crossed the line in ninth place.
The MotoGP World Championship leader, Marc Marquez, crashed from the lead of the Sprint Race and was one of three riders to not finish.
MotoGP San Marino, Full Sprint Race Results:
| 2025 San Marino MotoGP | Misano World Circuit Marco Simoncelli | Sprint Race Results | Round 16 of 22 | |||||
| Pos | Name | Nat. | Team | Bike | Gap |
| 1 | Marco Bezzecchi | ITA | Aprilia Racing | Aprilia RS-GP | |
| 2 | Alex Marquez | ESP | BK8 Gresini Racing MotoGP | Ducati GP24 | +1.000 |
| 3 | Fabio di Giannantonio | ITA | Pertamina Enduro VR46 Racing Team | Ducati GP25 | +2.551 |
| 4 | Franco Morbidelli | ITA | Pertamina Enduro VR46 Racing Team | Ducati GP24 | +3.526 |
| 5 | Pedro Acosta | ESP | Red Bull KTM Factory Racing | KTM RC16 | +6.834 |
| 6 | Fermin Aldeguer | ESP | BK8 Gresini Racing MotoGP | Ducati GP24 | +6.960 |
| 7 | Luca Marini | ITA | Honda HRC Castrol | Honda RC213V | +9.307 |
| 8 | Jorge Martin | ESP | Aprilia Racing | Aprilia RS-GP | +11.027 |
| 9 | Raul Fernandez | ESP | Trackhouse Racing | Aprilia RS-GP | +11.594 |
| 10 | Enea Bastianini | ITA | Red Bull KTM Tech3 | KTM RC16 | +12.928 |
| 11 | Johann Zarco | FRA | LCR Honda Castrol | Honda RC213V | +15.490 |
| 12 | Ai Ogura | JPN | Trackhouse Racing | Aprilia RS-GP | +15.600 |
| 13 | Pecco Bagnaia | ITA | Ducati Lenovo Team | Ducati GP25 | +16.129 |
| 14 | Jack Miller | AUS | Prima Pramac Racing | Yamaha M1 | +16.727 |
| 15 | Maverick Vinales | ESP | Red Bull KTM Tech3 | KTM RC16 | +16.861 |
| 16 | Miguel Oliveira | POR | Prima Pramac Racing | Yamaha M1 | +17.576 |
| 17 | Alex Rins | ESP | Monster Energy Yamaha | Yamaha M1 | +18.716 |
| 18 | Augusto Fernandez | ESP | Yamaha Factory Racing Team | Yamaha M1 | +27.893 |
| 19 | Somkiat Chantra | THA | LCR Honda IDEMITSU | Honda RC213V | +28.333 |
| DNF | Brad Binder | RSA | Red Bull KTM Factory Racing | KTM RC16 | |
| DNF | Marc Marquez | ESP | Ducati Lenovo Team | Ducati GP25 | |
| DNF | Fabio Quartararo | FRA | Monster Energy Yamaha | Yamaha M1 | |
