Marc Marquez dominated the opening session of the weekend at the Lusail International Circuit.
The fourth round of the MotoGP World Championship started in a familiar way in Qatar. Once again, it was Marc Marquez who set the pace in Free Practice One on the factory Ducati.
Pertamina Enduro VR46 Racing Team rider Fabio di Giannantonio ended the afternoon session in second. However, the Italian was over 0.5 seconds behind Marquez's best lap time.
The final Ducati GP25 rider of Francesco Bagnaia, ended Free Practice One in third place. The Italian had a better Friday afternoon than he had in the previous few rounds.
Alex Marquez continued the Ducati domination in Free Practice One as he ended the afternoon in fourth.
The top non-Ducati rider was Maverick Vinales on the Red Bull KTM Tech3 machine. The Spaniard ended the session in fifth place on the KTM RC16.
The Ducati domination continued outside of the top five as Franco Morbidelli was in sixth and Fermin Aldeguer was in seventh.
Honda HRC Castrol continue to find themselves in the top ten as Joan Mir ended the session in eighth.
The top Aprilia rider at the end of the opening session of the weekend was Marco Bezzecchi on the RS-GP.
Completing the top ten was Pedro Acosta on the Red Bull KTM Factory Racing machine.
The reigning World Champion, Jorge Matin, did make his return in Free Practice One but ended the session in 20th.
MotoGP Qatar, Full Free Practice One Results:
| 2025 Qatar MotoGP | Lusail International Circuit | Free Practice One Results | Round 4 of 22 | |||||
| Pos | Name | Nat. | Team | Bike | Times |
| 1 | Marc Marquez | ESP | Ducati Lenovo Team | Ducati GP25 | 1:52.288 |
| 2 | Fabio di Giannantonio | ITA | Pertamina Enduro VR46 Racing Team | Ducati GP25 | 1:52.801 |
| 3 | Pecco Bagnaia | ITA | Ducati Lenovo Team | Ducati GP25 | 1:52.871 |
| 4 | Alex Marquez | ESP | BK8 Gresini Racing MotoGP | Ducati GP24 | 1:52.945 |
| 5 | Maverick Vinales | ESP | Red Bull KTM Tech3 | KTM RC16 | 1:53.162 |
| 6 | Franco Morbidelli | ITA | Pertamina Enduro VR46 Racing Team | Ducati GP24 | 1:53.193 |
| 7 | Fermin Aldeguer | ESP | BK8 Gresini Racing MotoGP | Ducati GP24 | 1:53.198 |
| 8 | Joan Mir | ESP | Honda HRC Castrol | Honda RC213V | 1:53.223 |
| 9 | Marco Bezzecchi | ITA | Aprilia Racing | Aprilia RS-GP | 1:53.225 |
| 10 | Pedro Acosta | ESP | Red Bull KTM Factory Racing | KTM RC16 | 1:53.297 |
| 11 | Fabio Quartararo | FRA | Monster Energy Yamaha | Yamaha M1 | 1:53.322 |
| 12 | Luca Marini | ITA | Honda HRC Castrol | Honda RC213V | 1:53.361 |
| 13 | Alex Rins | ESP | Monster Energy Yamaha | Yamaha M1 | 1:53.430 |
| 14 | Johann Zarco | FRA | LCR Honda Castrol | Honda RC213V | 1:53.477 |
| 15 | Ai Ogura | JPN | Trackhouse Racing | Aprilia RS-GP | 1:53.507 |
| 16 | Augusto Fernandez | ESP | Prima Pramac Racing | Yamaha M1 | 1:53.517 |
| 17 | Brad Binder | RSA | Red Bull KTM Factory Racing | KTM RC16 | 1:53.651 |
| 18 | Enea Bastianini | ITA | Red Bull KTM Tech3 | KTM RC16 | 1:53.726 |
| 19 | Jack Miller | AUS | Prima Pramac Racing | Yamaha M1 | 1:54.107 |
| 20 | Jorge Martin | ESP | Aprilia Racing | Aprilia RS-GP | 1:54.112 |
| 21 | Raul Fernandez | ESP | Trackhouse Racing | Aprilia RS-GP | 1:54.114 |
| 22 | Somkiat Chantra | THA | LCR Honda IDEMITSU | Honda RC213V | 1:54.364 |
